Research Articles
Beyond Completeness: A Guide to CheckM2 for Accurate Strain-Level MAG Quality Assessment
This article provides a comprehensive guide for researchers and bioinformaticians on utilizing CheckM2 for strain-level quality assessment of Metagenome-Assembled Genomes (MAGs).
CheckM Explained: The Essential Guide to Assessing MAG Quality for Biomedical Research
This comprehensive guide explores CheckM, the standard tool for evaluating Metagenome-Assembled Genome (MAG) completeness and contamination.
CRISPRi for Functional Genomics in Bacteria: A Comprehensive Guide for Researchers and Drug Developers
This article provides a detailed, practical guide to CRISPR interference (CRISPRi) for functional genomics studies in bacterial systems.
CRISPR Spacer Analysis: Decoding Host-Phage Battles for Next-Gen Therapies
This article provides a comprehensive guide to CRISPR spacer analysis, a critical methodology for investigating host-phage interactions and microbial ecology.
Unlocking Host Defense: A Comprehensive Guide to CRISPR Screens for Resistance Gene Discovery
This article provides a detailed guide for researchers, scientists, and drug development professionals on employing CRISPR-based functional genomics screens to identify host resistance genes.
COG-Based Metabolic Pathway Reconstruction: A Comprehensive Guide for Systems Biology and Drug Discovery
This article provides a detailed, current exploration of Clusters of Orthologous Groups (COG) as a foundational framework for reconstructing metabolic networks in both model and non-model organisms.
COG vs eggNOG: A Comparative Guide for Functional Genomics in Biomedical Research
This comprehensive analysis compares the COG (Clusters of Orthologous Groups) and eggNOG (evolutionary genealogy of genes: Non-supervised Orthologous Groups) databases, critical tools for functional annotation and orthology prediction.
COG Phyletic Pattern Analysis: A Comprehensive Guide for Identifying Essential Genes and Novel Drug Targets
This article provides a detailed guide to COG (Clusters of Orthologous Groups) phyletic pattern analysis, a powerful comparative genomics method.
COG Functional Prediction vs. Experimental Validation: Bridging the Gap in Drug Discovery and Target Identification
This article provides a comprehensive analysis for researchers and drug development professionals on the evolving landscape of Clusters of Orthologous Genes (COG) functional annotation.
COG Database Decoded: The Complete Guide to Clusters of Orthologous Groups for Functional Annotation & Drug Discovery
This definitive guide provides researchers and drug development professionals with a comprehensive exploration of the Clusters of Orthologous Groups (COG) database.